Showa Denko America

This application note demonstrates how the use of DCM in particular had a dramatic effect on the separation and afforded conditions that could be further adapted to a preparative scale application.

Wednesday and Thursday, June 29 and 30, 2022 Day 1: 8:00am – 11:15am EDT Day 2: 8:00am – 11:15am EDT Learn about the latest novel analytical techniques and workflows that help analysts obtain the results they are looking for in “real world” situations involving small molecules in the pharmaceutical sector and analysts analyzing small molecules in the environment.

This technical article outlines the analysis of long-chain oligonucleotides utilizing a simple eluent containing acetonitrile with a relatively low level of salt and no ion-pair reagent.

The SI-36 4D does not require organic solvent to achieve the separation. Gradient conditions and phosphate ions are eluted within 15 minutes, so analysis time is short.

Monovalent and divalent cations in tap water were analyzed by IC YS-50.

Oxyhalides and anion standards in tap water were analyzed successfully using IC SI-52 4E. This is applicable to analyzing sources like rain, river water, and runoff.

The application successfully separates the 7 typical ions including F-, Cl-, NO2-, Br-, NO3-, PO43-, and SO42-, and it fulfills US EPA Method 300.1 (A) requirements.

The seven main anions can be separated quickly using the IC NI-424 column. Improvement has been made in the separation of chloride and nitrite ions.

Three variable lengths of oligo-DNA and phosphorothioated oligo-DNA separated without an ion pair reagent, using the Shodex™ HILICpak™ VT-50 2D.

MALS with SEC improves the efficiencies of the analysis of bionanoparticles that are difficult to be differentiated from the impurities during the purification process. 

Fermentation can be quickly monitored in foods using the Shodex rapid sugar series.

Statins were analyzed without using reversed phase mode separation nor ion-pairing reagents.

Shodex RSpak DE-413L is suitable for the analysis of water-soluble vitamins in a single run.

Shodex HILICpak VT-50 is suitable for the analysis of phosphorous-containing amino acids herbicids including glyphosate, glufosinate and their metabolites using ESI-MS detection.

Antibody molecular weight analysis can now be easily performed on the Shodex PROTEIN LW-803.

Shodex HILICpak VT-50 is suitable for the analysis of phosphorous-containing amino acids herbicids including glyphosate, glufosinate and their metabolites using ESI-MS detection.

Antibody molecular weight analysis can now be easily performed on the Shodex PROTEIN LW-803.

Shodex RSpak DE-413L is suitable for the analysis of water-soluble vitamins in a single run.

30mer oligonucleotides were analyzed with the Shodex HILICpak VN-50 coupled with LC/UV/ESI-MS detection without the need of ion-pair reagents.

Fermentation can be quickly monitored in foods using the Shodex rapid sugar series.

Living organisms (yeast and bacteria) were not identified as the agents that produced or spoiled common food items until the 19th century. Baking, especially of bread, was among the first industries to be transformed by the emerging scientific understanding of fermentation. The introduction of commercialized yeast in the early 20th century steadily reduced the time needed to bake bread both at home and on the production line, making way for modern packaged breads.