Achieving efficient analyte transfer between columns is critical to gaining the benefits of multidimensional GC.
Tony Taylor
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Tony Taylor is Group Technical Director of Crawford Scientific Group and CHROMacademy. His background is in pharmaceutical R&D and polymer chemistry, but he has spent the past 20 years in training and consulting, working with Crawford Scientific Group clients to ensure they attain the very best analytical science possible. He has trained and consulted with thousands of analytical chemists globally and is passionate about professional development in separation science, developing CHROMacademy as a means to provide high-quality online education to analytical chemists. His current research interests include HPLC column selectivity codification, advanced automated sample preparation, and LC–MS and GC–MS for materials characterization, especially in the field of extractables and leachables analysis.
Articles by Tony Taylor
Ion-exchange chromatography (IEC) is based on the different affinities of analyte and eluent counterions for the oppositely charged ionic functional groups on the stationary-phase surface of an exchange resin. Depending on the charge of the surface electrostatic groups, the resin could be either an anion exchanger (positively charged stationary phase) or a cation exchanger (negatively charged stationary phase).
Gradients can provide improved peak shape, higher efficiency, and sometimes altered selectivity and improved resolution.
Analytical method validation is the process of demonstrating that a method does what it is intended to do.
Can databases of column characteristics be used to help with HPLC column selection ahead of method development?
A look at the process of forming radical cations for analysis in GC–MS and the role of various ion source components
Strategies for reducing analysis time in capillary gas chromatography
The secret to electrospray ionization lies in three key steps.
This new column explains the essentials of key methods in separation science. This month: hydrophilic interaction chromatography.
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