Tony Taylor

Tony Taylor

Tony Taylor is Group Technical Director of Crawford Scientific Group and CHROMacademy. His background is in pharmaceutical R&D and polymer chemistry, but he has spent the past 20 years in training and consulting, working with Crawford Scientific Group clients to ensure they attain the very best analytical science possible. He has trained and consulted with thousands of analytical chemists globally and is passionate about professional development in separation science, developing CHROMacademy as a means to provide high-quality online education to analytical chemists. His current research interests include HPLC column selectivity codification, advanced automated sample preparation, and LC–MS and GC–MS for materials characterization, especially in the field of extractables and leachables analysis.

Articles by Tony Taylor

In this LCGC blog, some words of wisdom are offered to help one avoid that panic situation of having to change the GC column or delay the analytical results.

The new General Chapter <621> does reflect the great work of the Pharmacopoeias in helping chromatographers to use more modern technology for their regulated methods, speeding up analysis, and reducing waste. The latest revision allows us to adjust column dimensions for gradient separations, which is a significant advance. Although these freedoms are welcomed, one must be very mindful of the requirements or limits of the allowable changes and the verification work that underpins our demonstration of equivalent performance of the adjusted method.

It is a fact that most of us will be experiencing rising helium costs, and in some cases, caps on supply, or an inability to initiate new supply contracts from providers. Based on my own experiences, and those of colleagues and contacts, I’ve prepared what I hope is a succinct and focused guide on the factors one needs to evaluate to properly inform the decision to switch, and what to expect on the implementation journey.

As chromatographers, our thoughts turn to the use of hydrogen as an alternative carrier gas, to ensure continuity of supply and reduce long-term costs.

As chromatographers, our thoughts turn to the use of hydrogen as an alternative carrier gas, to ensure continuity of supply and reduce long-term costs.

The ability to predict issues and highlight unusual method parameters, before ever entering the laboratory, allows you to be alert for potential issues with a separation, or to change the method (where applicable) prior to initiating any experimentation. These detective skills, when applied in retrospect, are also invaluable for troubleshooting problems with the chromatographic separation or quantitative results.

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