The Application Notebook-09-01-2019

The Application Notebook

This application note describes the determination of the triphenylmethane dyes Malachite Green and Crystal Violet and their metabolites from the aquaculture samples brown trout, shrimp, and tuna using dispersive SPE (dSPE) with CHROMABOND QuEChERS mixes for sample clean-up.

The Application Notebook

Demonstratation of the glycopeptide enrichment efficiency of iSPE®-HILIC material for glycoproteomics applications using a well characterized glycoprotein standard.

The Application Notebook

This application note details an optimized method for the extraction and cleanup of pesticide residues from coffee using a QuEChERS extraction procedure followed by a silica gel SPE cleanup.

In this study, AF4-MALS-ICP-MS was applied to characterize four commercial tattoo inks: outlining black, purple deep violet, green grasshopper, and blue ice.

The Application Notebook

In this study, we developed a simple dilute-and‑shoot method that provides a fast 3.5-min analysis of fentanyl and related compounds (norfentanyl, acetyl fentanyl, alfentanil, butyryl fentanyl, carfentanil, remifentanil, and sufentanil) in human urine by LC–MS/MS using a Raptor Biphenyl column.

The Application Notebook

Sphingolipids are major components forming biological membranes, and they serve as intracellular signalling molecules. It is important to measure the amount of these molecules in biological samples because they have a massive influence on various metabolic diseases such as obesity, diabetes, and Alzheimer’s disease. Recently, an improved method using a YMC-Triart C18 metal-free column was reported by Dr. Gowda et al.

The Application Notebook
Pharmaceutical/Drug Discovery

September 01, 2019

In this application note, two commercially available samples were analyzed in the ASTRA® software by SEC coupled to a multi-angle light scattering (MALS) detector (DAWN®), a refractive index detector (Optilab®), and a differential viscosity detector (ViscoStar®).