The Application Notebook-09-01-2019

The Application Notebook

Determination of Triphenylmethane Dyes from Aquaculture Samples

September 01, 2019

Food and Beverage

32

9

This application note describes the determination of the triphenylmethane dyes Malachite Green and Crystal Violet and their metabolites from the aquaculture samples brown trout, shrimp, and tuna using dispersive SPE (dSPE) with CHROMABOND QuEChERS mixes for sample clean-up.

Analysis of Fentanyl and Its Analogues in Human Urine by LC–MS/MS

September 01, 2019

Medical/Biological

32

9

In this study, we developed a simple dilute-and‑shoot method that provides a fast 3.5-min analysis of fentanyl and related compounds (norfentanyl, acetyl fentanyl, alfentanil, butyryl fentanyl, carfentanil, remifentanil, and sufentanil) in human urine by LC–MS/MS using a Raptor Biphenyl column.

LC–MS/MS Analysis of Sphingophospholipids Using a Metal-Free Column

September 01, 2019

Medical/Biological

32

9

Sphingolipids are major components forming biological membranes, and they serve as intracellular signalling molecules. It is important to measure the amount of these molecules in biological samples because they have a massive influence on various metabolic diseases such as obesity, diabetes, and Alzheimer’s disease. Recently, an improved method using a YMC-Triart C18 metal-free column was reported by Dr. Gowda et al.

Characterization of PLGA Using SEC-MALS-IV

September 01, 2019

Pharmaceutical/Drug Discovery

32

9

In this application note, two commercially available samples were analyzed in the ASTRA® software by SEC coupled to a multi-angle light scattering (MALS) detector (DAWN®), a refractive index detector (Optilab®), and a differential viscosity detector (ViscoStar®).