LCGC Europe-01-01-2005

In this article, the authors present a simple high performance liquid chromatographic procedure for the determination of bendroflumethiazide (BFMT) in pharmaceutical formulations and urine samples. They demonstrate how the lack of an organic solvent in the mobile phase reduces the risk of environmental contamination and human toxicity.

In this first of a two-part series, John Hinshaw discusses the relative effects that inlet pressures and oven temperatures have on capillary gas chromatography.

In this article, the author describes the development of a simple enzymatic reactor, which also functions as a microdevice that combines both preconcentration and enzymatic digestion in the nano-electrospray emitter, and its interfacing with a mass spectrometer.

This month, John Dolan looks at how changes in retention time can help to identify the source of some LC problems and demonstrates what can be learned from observing how the retention varies.