LCGC Europe-03-01-2013

A panel of experts discuss the latest trends in sample preparaion.

The aim of this work was to find the optimal conditions to achieve sufficient limits of detection (LOD) that would permit the detection of neurotransmitters by LC–MS–MS in biological samples. An optimized HILIC–ESI–MS–MS system for the analysis of the 12 selected compounds was proposed.

This article describes a new analytical method for the global profiling of molecular lipids in biological samples, with particular emphasis on the plasmalogen lipids.

LCGC Europe
Columns/Articles

March 01, 2013

In contrast to isocratic separations, gradient elution can sometimes seem to be counter-intuitive. Yet with the proper perspective, the things we intuitively understand about isocratic methods apply in a similar manner to gradients.

LCGC Europe
Columns/Articles

March 01, 2013

Various gas flow measurement methods in the laboratory for GC users are compared.

A systematic approach for the identification of nontargeted species using nominal and accurate mass data searching both mass spectral and "spectral-less" databases is described.

Issue PDF
LCGC Europe

March 01, 2013

Click the title above to open the LCGC Europe March 2013 regular issue, Vol 26 No 3, in an interactive PDF format.