LCGC Europe-04-01-2015

This article describes a simple and rapid LC–MS method for evaluation of caffeine, taurine, and aspartame in teas, soft drinks, and energy drinks using HPLC coupled with electrospray ionization mass spectrometry detection and MISER analysis.

Spreadsheet computer simulations can identify the influencing factors for the set-up of a calibration function such as the number of calibration points and their distribution or the position of the experimental points. By using a Monte Carlo approach, the quality of the experimental results (bias and standard deviation) can be studied under different conditions. This article presents a spreadsheet for the simulation of unweighted and weighted linear least-squares fit.

When converting methods from LC to UHPLC, don’t get confused by flow-rate settings.

Our annual review of new liquid chromatography columns and accessories, introduced at Pittcon and throughout the previous year. This year, Michael Swartz, former author of our “Innovations in HPLC” and “Validation Viewpoint” columns, steps in as a guest columnist to write the review.

This instalment highlights some of the new HPLC systems, modules, accessories, and related technology introduced at Pittcon this year.

Event: 21st International Symposium on Separation Sceinces (21st ISSS 2015)

Click the title above to open the LCGC Europe April 2015 regular issue, Vol 28, No 4, in an interactive PDF format.