A review of the history and fundamentals for determining and reporting limit of detection (LOD) for analytical instruments and methods. Includes a discussion of the International Union of Pure and Applied Chemistry (IUPAC) and propagation of errors methods used for calculating LOD, and explains the limitations of the IUPAC method in modern chromatography.
This instalment focuses on basic concepts in extracolumn dispersion (ECD) that occurs in high performance liquid chromatography (HPLC) systems, and the impact of this dispersion on the performance of columns of different dimensions and efficiencies.
This article discusses innovation around the molecular structure of polymeric materials—an indispensable part of modern society—with a specific focus on sustainability. This field of research, so-called molecular correlative material characterization (MCMC), will enhance the transition into new sustainable functional copolymers.