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July 2022 | LCGC North America
Development of a System Suitability Test for Two-Dimensional Liquid Chromatography
July 01, 2022
Column: LC Troubleshooting
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7
As two-dimensional liquid chromatography (2D-LC) becomes more widely used, system suitability tests (SSTs) become even more important.
Improved Performance of UHPLC–MS Hyphenated Systems
July 01, 2022
Column: Column Watch
40
7
With a new prototype, we explore how to improve the resolution power and usability of LC–MS instruments for routine analysis in pharmaceutical applications.
Is the Solution Dilution? Hidden Uncertainty in Gas Chromatography (GC) Methods
July 01, 2022
Column: GC Connections
40
7
Hidden uncertainties in quantitative methods may make data look more precise and accurate than they really are. Take particular care when using dilution, which can increase experimental uncertainty.
Quantitative Analysis of PFAS in Milk, Infant Formula, and Related Ingredients Using Liquid Chromatography–Tandem Mass Spectrometry
July 01, 2022
Focus on Food Analysis
40
7
This method for PFAS analysis in milk and infant formula is robust, reliable, and reproducible, with scope to expand the list of PFAS in the future.
Whence the Next Generation of Macromolecular Separations Scientists?
July 01, 2022
40
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Developing and building a talent base in macromolecular separations should be a priority for employers. Here’s why.
A Full Scan Data Review Tool to Match the Speed of Acoustic Ejection Mass Spectrometry
July 01, 2022
Peer-Reviewed Article
40
7
Acoustic ejection mass spectrometry (AEMS) has recently emerged as the premier ultrahigh-throughput mass spectrometric methodology for drug discovery and related fields.
The Crucial Step in Every Analytical Workflow: Sample Preparation—Are We Ready For a Growing Area of Intact Protein Analysis?
July 01, 2022
40
7
New sample preparation workflows for intact proteins in biological matrices are needed. We hope that others will join in this important field of research.