LCGC North America-02-01-2008

LCGC North America
Validation Viewpoint

February 01, 2008

This month's "Validation Viewpoint" installment highlights some method validation guidelines used in developing and validating dissolution test procedures.

LCGC North America
Departments

February 01, 2008

During the last several years, the GC market has experienced strong growth in part because of new product introductions, growth in the petroleum sector, and increased opportunities in various geographies. To shed light on and determine the many realities and trends of the current GC instruments market, Strategic Directions International conducted a global survey of gas chromatography (GC and GC-MS) users. The survey was designed for individuals who are currently using a wide array of GC instruments and consumables, including aftermarket software, components, and accessories. The data were collected over the phone and by an internet-based survey. When necessary, the internet survey was followed up with direct telephone interviews of the appropriate respondents to further clarify answers.

LCGC North America
Column Watch

February 01, 2008

In 2001, the second glossary of common and not-so-common terms and "buzz words" for reference to HPLC columns and column technology was published. It is time for an update since new terms have arisen or, in some cases, their original meanings have expanded or changed.

This month, guest columnists Kind and Fiehn discuss small-molecule structure elucidation (excluding peptides) using hyphenated chromatographic techniques, mass spectrometers, and other spectroscopic detectors.

LCGC North America
LC Troubleshooting

February 01, 2008

Reversed-phase liquid chromatography (LC) is a simple and easy-to-use technique that will give satisfactory separations for the samples that most of us encounter. Here, John Dolan examines the pros and cons of this technique.

Departments
LCGC North America

February 01, 2008

Malvern Instruments Acquires Viscotek Corporation; Thermo Fisher Scientific Wins 2007 Frost and Sullivan Award; The Kinesis Group Acquires Abimed Analysen

LCGC North America

This article describes the method development and performance characteristics of the validated LFI assay and evaluates stability in human plasma.

The authors use GPC coupled online to multiangle laser light scattering, refractive index, and ultra violet (UV) detectors for the characterization of Acacia gum (gum arabic).