LCGC North America-10-01-2004
LCGC North America
Gradient Performance Checks
October 01, 2004
LC Troubleshooting
22
10
Just how good are your gradients?
Coupling Capillary Isoelectric Focusing with Mass Spectrometry
October 01, 2004
Directions in Discovery
22
10
This month'ss "Directions in Discovery" column discusses current work in the use of capillary isoelectric focusing and mass spectrometry as a multidimensional separation technique for proteomic studies.
Validation and Implementation of In-Process Control HPLC Assays for Active Pharmaceutical Ingredients
October 01, 2004
News
22
10
The authors describe a sensible approach for validation and implementation of HPLC IPC assays.
Hydrophilic Interaction Chromatography Using Silica Columns for the Retention of Polar Analytes and Enhanced ESI-MS Sensitivity
October 01, 2004
News
22
10
The use of a silica column for HILIC is examined, including mechanistic studies of analyte retention on silica in aqueous-organic mobile phases.
Practical Tips on Preparing Plasma Samples for Drug Analysis Using SPME
October 01, 2004
Sample Prep Perspectives
22
10
This month'ss guest authors review the application of solid-phase SPME to the analysis of drugs in human plasma.
Finding a Needle in a Haystack
October 01, 2004
GC Connections
22
10
This month's "GC Connections" examines the various ways – and their attendant benefits and drawbacks – with which chromatographers and chromatography data-handling systems locate and measure peaks