Hydrophilic Interaction Chromatography Using Silica Columns for the Retention of Polar Analytes and Enhanced ESI-MS Sensitivity

Alden,Bonnie;Mazzeo,Jeffrey;Wagrowski-Diehl,Diane;Grumbach,Eric;Iraneta,Pamela;

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Hydrophilic Interaction Chromatography Using Silica Columns for the Retention of Polar Analytes and Enhanced ESI-MS Sensitivity

Published on: October 1, 2004

Bonnie Alden, Jeffrey R. Mazzeo, Diane M. Wagrowski-Diehl, Eric S. Grumbach, Pamela Iraneta

LCGC North America

LCGC North America, LCGC North America-10-01-2004, Volume 22, Issue 10

The use of a silica column for HILIC is examined, including mechanistic studies of analyte retention on silica in aqueous-organic mobile phases.