LCGC North America-10-01-2018

LCGC North America

Vol 36 No 10 LCGC North America October 2018 Regular Issue PDF

October 01, 2018

LCGC 1018 Issue PDF

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Click the title above to open the LCGC North America October 2018 issue in an interactive PDF format.

Highlights from the HPLC 2018 Symposium

October 01, 2018

Column Watch

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Topics that stood out at HPLC 2018 include advances in large-molecule separations, multidimensional separations, 3D printing, chiral separations, and HILIC. Also, many speakers addressed separation fundamentals, including ways to increase speed, generate higher throughput, and add selectivity.

Mixing and Mixers in Liquid Chromatography—Why, When, and How Much? Part I, The Pump

October 01, 2018

LC Troubleshooting

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Many LC users are unclear what happens when we combine two (or more) flow streams in LC systems, and when mixers are needed to blend the fluids. This discussion explains why mixers are needed, and when and how you might consider using something other than the default mixer setting.

Modern Trends and Best Practices in Mobile-Phase Selection in Reversed-Phase Chromatography

October 01, 2018

Perspectives in Modern HPLC

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Modern trends in LC mobile-phase selection and preparation include using simpler mobile phases, increased use of MS-compatible mobile phases, and eliminating filtration and certain mobile-phase additives. Here, we discuss those and other trends and best practices, as well as the fundamentals behind them.

Molecular Imprinting for Sample Preparation

October 01, 2018

Peer-Reviewed article

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Molecularly imprinted polymers can replace conventional sorbent materials in sample preparation techniques such as solid-phase extraction (SPE), solid-phase microextraction (SMPE), and matrix solid-phase dispersion (MSPD), offering increased selectivity over the target analytes.

The Quest for Greener Sample Preparation in Food Analysis

October 01, 2018

Focus on Food Analysis

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Elena Ibañez is determined to make sample preparation for food analysis not only more environmentally friendly but also more efficient, as she explores approaches that simplify solvent selection, increase solvent selectivity, and lessen the role of chemical solvents.

Tips for Successful GC–MS Tuning and Optimization

October 01, 2018

The Essentials

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Proper tuning and calibration of instruments ensure their peak response and an exact mass-to-charge ratio and ion abundance measurement.