Special Issues-11-01-2016

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Advances in Biopharmaceutical Analysis

Pat Sandra;Koen Sandra
November 1st 2016
ArticleArticle

An introduction from the guest editors of this special supplement

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Modern Column Technologies for the Analytical Characterization of Biopharmaceuticals in Various Liquid Chromatographic Modes

Szabolcs Fekete;Jean-Luc Veuthey;Davy Guillarme
November 1st 2016
ArticleArticle

The recent trends in column technology for reversed-phase LC, SEC, ion-exchange chromatography, and HIC for analysis of biopharmaceuticals are critically discussed.

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Monoclonal Antibodies and Biosimilars—A Selection of Analytical Tools for Characterization and Comparability Assessment

Isabel Vandenheede;Pat Sandra;Koen Sandra;Emmie Dumont
November 1st 2016
ArticleArticle

This article presents a selection of state-of-the-art analytical tools for mAb characterization and comparability assessment.

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Higher Order Mass Spectrometry Techniques Applied to Biopharmaceuticals

Christian G. Huber
November 1st 2016
ArticleArticle

An outline of the basic principles of MS techniques used to investigate higher order structural features of biopharmaceuticals, as well as some insights into applications relevant to the pharmaceutical industry.

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Analyzing Host Cell Proteins Using Off-Line Two-Dimensional Liquid Chromatography–Mass Spectrometry

Pat Sandra;Koen Sandra;Alexia Ortiz
November 1st 2016
ArticleArticle

The use of off-line 2D-LC–MS for the characterization of HCPs and their monitoring during downstream processing

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Advances in Liquid Chromatography–Tandem Mass Spectrometry (LC–MS/MS)-Based Quantitation of Biopharmaceuticals in Biological Samples

Nico C. van de Merbel
November 1st 2016
ArticleArticle

The technical requirements for a successful LC–MS/MS method for the quantitation of biopharmaceuticals are presented and the advantages and disadvantages compared to ligand-binding assays are evaluated.

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Vol 34 No s11 LCGC North America November 2016 Advances in Biopharmaceutical Analysis Supplement PDF

November 1st 2016
ArticleIssue PDF

Click the title above to open the LCGC North America November 2016 Advances in Biopharmaceutical Analysis Supplement, Vol 34 No s11, in an interactive PDF format.