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Derivatization of the analytes targeted in an HPLC-ESI-MS separation can help improve detection limits.

Love it or hate it, cheese is everywhere in western diets, but have you ever wondered when cheese production began?

Sigma approaches are used to reduce variations and improve quality when performing chromatographic procedures. The terminology of this approach is introduced, together with illustrative examples and suggestions.

A team of scientists at the University of Regensburg (Regensburg, Germany) has discovered a microbial defence method used by emerald cockroach wasp (Ampulex compresa F.) larvae to prevent its food source, the cockroach, from putrefying.1

A panel of experts discuss the latest trends in sample preparaion.

Peaks of Interest

Benefits of elevated-temperature seperations in LC are discusssed.

MS: The Practical Art Editor Kate Yu interviews Fred McLafferty about his pioneering career in mass spectrometry

The first three important stages in any GC analysis are explained.

A systematic approach for the identification of nontargeted species, searching both mass spectral and "spectra-less" databases

Answers to common questions about operational qualification software.

How to use small columns to test potential biphasic liquid systems for use in large-scale countercurrent chromatography separations

The Swiss-based Global Discovery Chemistry platform of the Novartis Institutes for BioMedical Research has an immediate opening for an accomplished PhD-qualified Chemist with significant work experience with a variety of chromatographic methods for the preparative separation, isolation, and purification of chemical substances.

HPLC2013 red and white image

A guide to using HPLC in an iterative form to clarify decision-making during method development

An interview with Fred McLafferty, professor emeritus at Cornell University, about his pioneering career in mass spectrometry

Short Courses

Thermo NA - Analysis of Cephalosporins on a Polar Endcapped C18 3 ?m Particle Column

Click here to view the complete LCGC Europe E-Newsletter from 1 February 2013

Thermo NA - Analysis of Non-Steroidal Anti-Inflammatory Drugs Using a Highly Pure, High Surface Area C18 HPLC Column

Thermo NA - An Improved HPLC Method for the Separation of Norethindrone and Mestranol with Progesterone as Internal Standard

ALMSCO EU - Analysis of polycyclic aromatic hydrocarbons from vehicle exhaust using TD?GC/TOF MS

LCGC has announced a major new partnership in China, with Sepu.net, the China Chromatography Network. Through this partnership, LCGC Asia Pacific will be distributed to more than 130,000 practicing chromatographers in Greater China.

Malvern Instruments (Malvern, UK) has opened a new applications laboratory in Sao Paulo, Brazil.

Click the title above to open the LCGC Europe February 2013 regular issue, Vol 26 No 2, in an interactive PDF format.

Click the title above to open the LCGC North America February 2013 regular issue, Vol 31 No 2, in an interactive PDF format.

Click the title above to open the LCGC North America February 2013 Application Notebook, Vol 31 No s2, in an interactive PDF format.

Thermo NA - LC-MS/MS Method for the Rapid Analysis of Five Artificial Sweeteners Using a Core Enhanced Technology Column