
In clinical and pharmaceutical testing, analkyses of drug compounds and their metabolites are often performed in complex biological matrices, such as plasma and whole blood.

In clinical and pharmaceutical testing, analkyses of drug compounds and their metabolites are often performed in complex biological matrices, such as plasma and whole blood.

Analytical Pixels Technology (APIX) (Grenoble, France) has teamed up with research organisations, CEA?Leti (Grenoble, France) and Caltech (California, USA).

The Microlute SPE sample preparation system from Porvair Sciences provides a faster, trouble-free alternative to cartridges for high throughput sample clean-up.

Agilent (California, USA) and Sera Prognostics (Utah, USA) have formed a strategic partnership to develop proteomic assays for the prediction of pregnancy complications. Sera Prognostics is a private biotechnology company that develops diagnostic tests for these risks.

Ultra-high sensitivity, expanded flexibility, increased stability and robustness - the new Nexera X2 UHPLC system targets routine analysis and applications in highly regulated environments demanding complex system setups.

Click here to view the complete E-Separation Solutions newsletter from February 14, 2013

Thermo NA - Determining Inorganic Cations in Wastewater with HPIC

Waters - Qualitative and Quantitative Analysis of β-carotene Using UPC2

Thermo Fisher Scientific (California, USA) has entered into a Technology Alliance Partnership agreement with the Barnett Institute, Northeastern University (Massachusetts, USA).

Waters EU - Using XP Columns to Modernize the USP Organic Impurities Analysis of Tioconazole

The United States Pharmacopeial Convention (USP) has added nearly 800 new records, mostly from 2011 and 2012, to its Food Fraud Database, increasing the size of the database by 60%. The original database contained 1,300 records, covering fraud reports issued between 1980 and 2010. The database compiles data taken from publicly available reports in both scholarly journals and general media, with key findings published in the Journal of Food Science (1).

Click here to view the complete LCGC Europe E-Newsletter from 8 February 2013

Bruker EU - Analysis of Microcystins in Drinking Water

Bruker NA - Analysis of Microcystins in Drinking Water

Thermo EU - Analysis of Non-Steroidal Anti-Inflammatory Drugs Using a Highly Pure, High Surface Area C18 HPLC Column

Thermo EU - Comparative Analysis of Cooking Oils Using a Solid Core HPLC Column

Thermo EU - Analysis of Cephalosporins on a Polar Endcapped C18 3 µm Particle Column

Thermo EU - An Improved HPLC Method for the Separation of Norethindrone and Mestranol with Progesterone as Internal Standard

Thermo EU - LC–MS-MS Method for the Rapid Analysis of Five Artificial Sweeteners Using a Core Enhanced Technology Column

Derivatization of the analytes targeted in an HPLC-ESI-MS separation can help improve detection limits.

Love it or hate it, cheese is everywhere in western diets, but have you ever wondered when cheese production began?

Sigma approaches are used to reduce variations and improve quality when performing chromatographic procedures. The terminology of this approach is introduced, together with illustrative examples and suggestions.

A team of scientists at the University of Regensburg (Regensburg, Germany) has discovered a microbial defence method used by emerald cockroach wasp (Ampulex compresa F.) larvae to prevent its food source, the cockroach, from putrefying.1

A panel of experts discuss the latest trends in sample preparaion.

Peaks of Interest

Benefits of elevated-temperature seperations in LC are discusssed.

MS: The Practical Art Editor Kate Yu interviews Fred McLafferty about his pioneering career in mass spectrometry

The first three important stages in any GC analysis are explained.

Polar lipids and other metabolites extracted from plasma from lean, diabetic, and obese Zucker rats were analyzed by flow injection using high resolution time of flight mass spectrometry. Metabolites were confidently identified and differences in the metabolite profiles determined.

A systematic approach for the identification of nontargeted species, searching both mass spectral and "spectra-less" databases