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An overview on the present state of analytical lipidomics is presented from the perspective of mass spectrometry (MS) and the MS strategies most frequently used in lipidomics are highlighted.

Bruker has announced the opening of a new major applications, training and service centre in Shanghai, China.

At the ASMS 2011 conference, Jim Jorgenson of the University of North Carolina shared his thoughts on current and potential future developments in LC that will affect the practice of LC?MS. Here are his views on particle size, superficially porous particles, monoliths, open-tubular columns, and questions of pressure and temperature.

High-definition screening by gas chromatography–mass spectrometry (GC–MS) is shown to be a viable option for the reliable identification of odorous compounds in pork.

A critical look into the future of imaging mass spectrometry is made by addressing some of the fundamental and technical challenges that still need to be overcome.

A selection of LC-MS products

Participants in this technology forum are Ling Bei, Patrik Appelblad and Dave Lentz of EMD Millipore; Nadine Boudreau of PharmaNet Canada; Diab Elmashni, Jeff Zonderman and Simon Szwandt of Thermo Fisher Scientific; and Debadeep Bhattacharya of Waters Corporation.

Ion mobility–mass spectrometry (IM-MS) is outlined as a separations method, several examples of the utility of IM-MS for complex biological measurements are illustrated, and the implications of this approach for systems biology research are discussed.

A method is illustrated for the simultaneous analysis of ethyl glucuronide and ethyl sulfate in human urine samples.

An overview on the present state of analytical lipidomics is presented from the perspective of mass spectrometry (MS) and the MS strategies most frequently used in lipidomics are highlighted.

LECO product profile

This study illustrates the versatility of a laser-induced acoustic desorption (LIAD) approach for volatilization of analytes in modern mass spectrometry.

The combination of GC with time-of-flight (TOF)-MS proves to be a successful approach for the challenging analysis of persistent organic pollutants in complex matrices such as sediment and fish samples.

Rules of thumb for isolating problems, determining problem sources, and developing a maintenance routine.

Discussion about the use of gas switching valves for column backflush and two-dimensional series-bypass applications

Agilent Product Profile

Developments in pulsed electrochemical detection are traced through the progression of its waveforms.

Method translation software enables conversion and improvement of GC methods.

Click the title above to open the LCGC North America July 2011 regular issue, Vol 29 No 7, in an interactive PDF format.

Green tea is drunk by many for the health benefits of the antioxidant catechins, which are thought to help fight heart disease and other conditions. The stability of these compounds is important for choosing the best storage conditions and determining an accurate shelf life. However, a study has revealed that they may not be as stable as was once thought.

BAC BV, a Dutch provider of antibody-based affinity purification technology, has announced a strategic collaboration with Life Technologies, a manufacturer of molecular diagnostic and research-use products, which will bring the range of BAC's CaptureSelect affinity ligand specificities to Life Technologies' Poros chromatography media and pre-packed HPLC columns.

CHROMacademy, CHROMmunity and The Column have won a Media Pioneer Award at the 2011 Specialist Media Show, for outstanding innovation and entrepreneurial achievement in specialist media.

As HPLC 2011 in Budapest is the first HPLC show since Thermo?s acquisition of Dionex, the company has been using the show to showcase a new expanded chromatography portfolio.

The Thermo Scientific Q Exactive benchtop Orbitrap system combines high-performance quadrupole precursor selection with high-resolution, accurate-mass (HR/AM) Orbitrap detection.

Agilent Product Profile

Synthetic cannabinoids, commonly found in ?herbal incense? brands were recently declared controlled substances by the US Drug Enforcement Agency. To assist the drug testing industry in detecting these substances, Agilent Technologies has produced a GC?MS compendium.

HPLC 2011: Day 3

Wednesday Morning Sessions