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LCGC Europe

Isotopic analysis of archaeological materials provides information on age and source, but analysis of single compounds isolated from artefacts can provide more accurate measurements and additional details. In this article, the authors provide a review of chromatographic separations of archaeological biomolecules for their analysis using accelerator mass spectrometry or isotope ratio mass spectrometry. The article concentrates primarily on studies involving carbon and nitrogen.

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LCGC Europe

This article describes the pros and cons of pSFC–MS and attempts to demonstrate its broad applicability to such fields as high-throughput analysis, purity assessment, structure characterization and purification. It concludes with a look at the potential of the technique in the future of analytical drug discovery.

LCGC Europe

A fast and easy-to-use method for the identifcation and determination of active anionic ingredients in toothpaste is presented using ion chromatography in combination with electrospray mass spectrometry. In this application, positive identification of glycerol, sorbitol, chloride, fluoride, sulphate, monofluorophosphate and polyphospates, in addition to citrate and saccharin, is achieved in one chromatographic run with a total analysis time of 22 min.

LCGC Europe

In the second instalment of this newly introduced column, Michael Balogh looks at resolution and mass accuracy as important considerations for determining the suitability of a mass spectrometer for an intended purpose.

LCGC North America

Valco Instruments Co., Inc. For more information, visit the company's website at www.valco.com.

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