Advancements to Take the Pain Out of Chromatographic Peak Integration

Peak detection and integration are fundamental tasks in chromatography. Chromatographers devote considerable time and efforts towards ensuring the accuracy and appropriateness of integration because this information is used for all subsequent calculations, such as calibrations, determining the purity of drug substances and analysis of unknowns.

Ideally, chromatographic peaks would be perfectly symmetrical with pronounced detector signal changes that clearly identify where the peak starts and ends. In reality, integration is much more complex and diverse because chromatographic data systems have to decipher many different variants and effects.

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