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Agilent microarrays have been used in a landmark research study on prenatal samples.
Agilent microarrays have been used in a landmark research study on prenatal samples. The study encompassed three years and 4400 samples and was designed to evaluate the accuracy and potential advantages of using microarray analysis over conventional karyotyping. Researchers from Emory University, Baylor College of Medicine, Columbia University and Signature Genomics all took part in the study.
Most of the samples were uncultured amniotic fluid and chorionic villi and all were sent to a reference lab for chromosome analysis.
The study represents an important milestone in understanding prenatal abnormalities. Dr Laird Jackson, Professor of Genetics, Department of Obstetric and Gynecology, Drexel University College of Medicine, commented, “This landmark research study on prenatal samples will have long-lasting implications to the research community. Microarrays allowed us to detect smaller aberrations compared to traditional karyotyping.”
Seventy one percent of samples were run on Agilent SurePrint CGH microarrays and Agilent software was used for data analysis. Agilent also assisted the research group in developing the arrays used in the study.