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|Articles|June 23, 2021
Avoiding Depurination During Trityl-on Purification v2
Author(s)Phenomenex, Inc.
Trityl-on methodologies for the analysis of crude synthetic oligonucleotides has many benefits however depurination during trityl-on methodologies can lead to nucleic acid damage. This technical note explores a new trityl-on procedure that minimizes the risk of depurination.
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