
|Articles|June 23, 2021
Comparing Performance of High-Throughput, Trityl-on RNA/DNA Purification Products v2
Author(s)Phenomenex, Inc.
Clarity QSP provides an alternative trityl-on approach for separating truncated sequences and synthetic contaminants from the protected full-length sequence. By incorporating a polymeric sorbent with a unique buffer formula, aborted fragments and synthetic contaminants are removed during sample loading offering a departure from the traditional RPC mechanism. Multiple buffers and gradient elutions are eliminated, thereby making Clarity QSP a 3-step product for trityl-on oligonucleotide purification.
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