|Articles|December 1, 2001

LCGC North America

  • LCGC North America-12-01-2001
  • Volume 19
  • Issue 12

Data Handling for Fast Chromatography — Qualitative Analysis

The November 2001 installment addressed requirements and potential problems associated with the acquisition of fast chromatography peaks at detectors and data-recording systems. Hinshaw continues the topic in this month's column and treats issues that involve qualitative data reduction after a chromatogram has been acquired.

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Product Showcase

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2001 Index of Authors and Subjects

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Chromatography Detects Toxins in Tea Samples
High-performance liquid chromatography-tandem mass spectroscopy (HPLC–MS/MS) chromatography reveals pyrrolizidine alkaloids (PA)/pyrrolizidine alkaloid N-oxides (PANO) toxin risks in 63 tea samples.
Figure 2. Split injection used to measure triplicate test of MTBE, hexane, o-xylene, and 1-methylnaphthalene comparing different solvents (methanol, methylene chloride) and column insertion distances starting with 0.5 mm, 5.0 mm, 10.0 mm, 15 mm, and 20.0 mm. Methanol had the best performance at the 5.0 mm insertion distance and methylene chloride looked slightly better at the 0.5 mm. We would still recommend not going below the 5.0 mm manufacturer recommended insertion distance.
Revisiting insertion distance for methanol and methylene chloride in GC analysis and confirming that insertion depth strongly affects response and reproducibility.