Paper spray-mass spectrometry vs. liquid chromtography-tandem mass spectrometry (LC-MS/MS): Can rapid screening rival the gold standard in ER drug testing?
|Articles|September 19, 2014
- The Column-09-18-2014
- Volume 10
- Issue 17
Detecting Microbial Compounds in Waterpipe Smoke
Author(s)Bethany Degg
Waterpipes have been used to smoke tobacco and other substances for more than four centuries, and are widely believed to be less harmful than cigarettes. In a new study published in the journal Science of the Total Environment, gas chromatography coupled to mass spectrometry (GC–MS–MS) was performed to show that waterpipe smoke can contain potentially harmful microbial compounds.
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Liquid chromatography-tandem mass spectrometry (LC-MS/MS) finds high fentanyl levels do not predict toxicity in tolerant users.
Gas chromatography-ion mobility spectrometry (GC-IMS) identifies odor markers that flag early mold growth in cigar tobacco.
Lorna Nisbet from the Leverhulme Research Centre for Forensic Science, discusses a GC–MS. technique developed to detect anabolic-androgenic steroids in e-cigarettes seized from Scottish prisons.
Kinjal Bhatt and Ina Varfaj trace their pull toward analytical science to a saturated chromatography peak and the moment their first chiral peaks separated.
Gérard Hopfgartner explains why pairing SFC with dopant-assisted APPI can match, or even beat, electrospray sensitivity, even at microflow LC rates.
Emma Macturk from LECO Corporation explains which forensic applications benefit from GC×GC’s greater peak capacity, and when the additional separation power may only provide limited benefits.
Koji Yamaguchi of the International University of Health and Welfare (Narita, Japan) discusses a novel derivatized liquid chromatography-tandem mass spectrometry (LC-MS/MS) method plus propofol glucuronide (PRG) marker which improves forensic propofol detection.
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