Experimental Combination of Method Development Strategies in a Working Environment of Different Instrumental Set-ups

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The Column

ColumnThe Column-03-18-2011
Volume 7
Issue 5

Experimental Combination of Method Development Strategies in a Working Environment of Different Instrumental Set-ups

Modelling of retention behaviour of pharmaceutical compounds has a long history. In recent times chromatography modelling software has been shown to considerably aid the application of Quality by Design (QbD) principles in the method development process, with the construction and evaluation of column and eluent design spaces.

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