GC Measurement of Nitrous Oxide in Exhaled Air

In a note recently published in Clincal Chemistry, researchers describe a method for detection of N2O in exhaled air by using gas chromatography (GC).

In a note recently published in Clincal Chemistry, researchers describe a method for detection of N2O in exhaled air by using gas chromatography (GC). According to the note, nitrous oxide is a relatively stable compound, present at ~310 nL/L in the atmosphere and is produced predominantly by microbial reduction of nitrate. This process, called denitrification, is the conversion of nitrate to gaseous nitrogen compounds, resulting in a product of nitrogen or nitrous oxide under most conditions.