Isocratic Separation of Acetaminophen, Phenylephrine, Chlorpheneramine and Dextromethorphan on Gemini C18

August 8, 2008

E-Separation Solutions

E-Separation Solutions-08-07-2008, Volume 0, Issue 0

In this note, we describe an isocratic method for the simultaneous determination of the four component cold remedy that can be used for high-throughput screening. For comparison, a gradient protocol and a two-step flow gradient under isocratic conditions are also explored.