The model context protocol (MCP) layer lets AI run mzmine mass spectrometry workflows; data stays local.
|Articles|August 8, 2008
E-Separation Solutions
- E-Separation Solutions-08-07-2008
- Volume 0
- Issue 0
Isocratic Separation of Acetaminophen, Phenylephrine, Chlorpheneramine and Dextromethorphan on Gemini C18
In this note, we describe an isocratic method for the simultaneous determination of the four component cold remedy that can be used for high-throughput screening. For comparison, a gradient protocol and a two-step flow gradient under isocratic conditions are also explored.
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Articles in this issue
about 18 years ago
Market Profile: Mass Spectrometry in North America and Europeabout 18 years ago
From the Editor: PharmSep Comes to Philadelphiaabout 18 years ago
Overcoming Compound Volatility with Sub-ambient ELSDabout 18 years ago
Technology Forum: Softwareabout 18 years ago
Ask the Editor: The Effect of Sample Diluent Ionic StrengthAdvertisement
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Ultrahigh-performance liquid chromatography–high-resolution tandem mass spectrometry (UHPLC-HRMS/MS) reveals a chemical imbalance behind alcohol-positive milk.
"Perspectives in HPLC" examines 5 long-held HPLC "rules" (mobile phase filtration, routine buffer use, avoiding pH near an analyte's pKa, defaulting to 4.6-mm columns, and relying on AI for early method development), showing with experimental evidence that each is conditional rather than universally true in modern small-molecule drug testing.
In this ninth part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor explores the reasons why mobile phase filtration is not needed.
A review of affinity chromatography methods for biopharmaceutical analysis.
Ultrahigh-performance liquid chromatography–ion mobility–quadrupole time-of-flight mass spectrometry (UHPLC–IM–QTOF MS) reveals seasonal chemical fingerprints in Scottish honey.
Markes International’s vacuum-assisted HiSorb extends analyte coverage for gas chromatography.
Gold-enhanced thin-layer chromatography–surface-enhanced Raman scattering (TLC–SERS) identifies toxic aromatics in firefighting water.
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