A new technique, using liquid chromatography-mass spectrometry (LC-MS), has now made it easier for scientists and researchers to obtain any information they need from very small amounts of blood.
A new technique, using liquid chromatography-mass spectrometry (LC-MS), has now made it easier for scientists and researchers to obtain any information they need from very small amounts of blood.
The technique, which was developed by a group of researchers from the University of Colorado led by anesthesiologist Jeffry Galinkin, uses a new method of screening miniscule amounts of dried blood for chemicals.
This new method will reportedly solve the current problem that researchers have faced with obtaining a sufficient amount of blood from infants to test for chemicals. According to Galinkin, drug dosing guides for infants is the primary priority for the researchers, however it is only one of many possible applications of the technique, which include diagnosing HIV or tuberculosis, and even testing for banned substances in athletes.
Inside the Laboratory: The Gionfriddo Group at the University at Buffalo
March 28th 2024In this edition of “Inside the Laboratory,” Emanuela Gionfriddo, PhD, an associate professor of chemistry at the University at Buffalo, discusses her group’s current research endeavors, including using solid-phase microextraction (SPME) coupled to liquid chromatography (LC) and gas chromatography (GC) to further understand the chemical relationship between environmental exposure and disease and elucidate micropollutants fate in the environment and biological systems.
Transferring Methods to Compact and Portable HPLC
February 14th 2024The current trend in laboratory equipment design is the miniaturization of laboratory instruments. Smaller-scale HPLC instruments offer benefits that cannot be matched by analytical-scale equipment, especially in the areas of portability, reduced fluid volumes, and reduced operating costs. Yet, the miniaturization of laboratory equipment has brought with it a unique set of challenges, including transferring methods to compact LC. Capillary LC expands the use of LC to applications not currently done using conventional LC in a wide array of application areas, including pharmaceutical, food and beverage, petrochemical, environmental, and oil and gas. Greg Ward, Axcend’s CEO wrote, “Customers want an HPLC system with a small footprint, low flow rates and green chemistry.” Join his podcast where he shares method transfer in these application areas.