Liquid chromatography-tandem mass spectrometry (LC-MS/MS) finds high fentanyl levels do not predict toxicity in tolerant users.
|Articles|December 6, 2011
- The Column-12-06-2011
- Volume 7
- Issue 22
Market Profile: GC‒MS
Gas chromatography?mass spectrometry (GC?MS) combines a gas chromatographic front-end separation with a mass spectrometer. For the most part, the gas chromatographs and mass spectrometers used are modular in design and relatively easily separable. GC?MS is the most widespread tandem technique in the analytical instrumentation industry, which are employed across many different industries, particularly for environmental, chemical and toxicological applications.
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Gas chromatography–mass spectrometry (GC–MS) combines a gas chromatographic front-end separation with a mass spectrometer. For the most part, the gas chromatographs and mass spectrometers used are modular in design and relatively easily separable. GC–MS is the most widespread tandem technique in the analytical instrumentation industry, which are employed across many different industries, particularly for environmental, chemical and toxicological applications.
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Instrumental Innovationsalmost 15 years ago
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Gas chromatography-ion mobility spectrometry (GC-IMS) identifies odor markers that flag early mold growth in cigar tobacco.
Lorna Nisbet from the Leverhulme Research Centre for Forensic Science, discusses a GC–MS. technique developed to detect anabolic-androgenic steroids in e-cigarettes seized from Scottish prisons.
Kinjal Bhatt and Ina Varfaj trace their pull toward analytical science to a saturated chromatography peak and the moment their first chiral peaks separated.
Gérard Hopfgartner explains why pairing SFC with dopant-assisted APPI can match, or even beat, electrospray sensitivity, even at microflow LC rates.
Emma Macturk from LECO Corporation explains which forensic applications benefit from GC×GC’s greater peak capacity, and when the additional separation power may only provide limited benefits.
Koji Yamaguchi of the International University of Health and Welfare (Narita, Japan) discusses a novel derivatized liquid chromatography-tandem mass spectrometry (LC-MS/MS) method plus propofol glucuronide (PRG) marker which improves forensic propofol detection.
Gas chromatography-mass spectrometry (GC-MS) coupled with headspace solid-phase microextraction )HS-SPME) links cocoa variety to chocolate aroma and flavor profiles.
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