From the Publisher: The Application Notebook: A Critical Market Barometer
The Application Notebook
Like any other segment of the world economy, current events and the realities of the world around us go a long way toward shaping the direction of chromatographic research and development, and consequently, the financial trends that have a direct impact on the industry in which we all live and work. In this sense, the LCGC Application Notebook has become something of a market barometer over the years.
Like any other segment of the world economy, current events and the realities of the world around us go a long way toward shaping the direction of chromatographic research and development, and consequently, the financial trends that have a direct impact on the industry in which we all live and work. In this sense, the LCGC Application Notebook has become something of a market barometer over the years.
Michael J. Tessalone
As anyone keeping up on current events will tell you, the worldwide news media has been full of stories concerning safe drinking water, EPA regulations, toy safety and the recent lead paint scare, and especially at this time of the year, gasoline prices. It may surprise some readers to see how quickly these issues, which may seem strictly sociopolitical on the surface, can make their way into the content of LCGC North America, and in particular, into this, the June issue of the LCGC Application Notebook. Just a quick glance at the table of contents will reveal a striking increase in the number of application notes dedicated to chromatographic methods aimed at increasing water purity, making toys safer for children, and developing new and more affordable biofuels to decrease dependence on traditional oil markets.
We are proud of what the Application Notebook has become over the years, and now, in addition to this issue serving as a valuable laboratory resource and a vehicle to connect vendors with customers, we feel confident stating that this issue has now become a critical market indicator as well — both for the chromatographic community and the economy at large. As always, for those who are interested, we have included information about submitting materials for our next supplement in this series, September 2008. This information can be found on "Call for Application Notes", and we invite you to contact us at the e-mail addresses listed in the masthead with any questions, comments, or feedback.
Enjoy the issue!
Michael J. Tessalone
Group Publisher
Measuring Procyanidin Concentration in Wines Using UHPLC
January 24th 2025Researchers from the University of Bordeaux (Villenave d'Ornon, France) report the development and validation of a rapid and quantitative analytical method measuring crown procyanidin concentration in red and white wines using ultra-high performance liquid chromatography (UHPLC) coupled with a ultra-high performance liquid chromatography (Q-TOF) mass spectrometer.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Testing Solutions for Metals and PFAS in Water
January 22nd 2025When it comes to water analysis, it can be challenging for labs to keep up with ever-changing testing regulations while also executing time-efficient, accurate, and risk-mitigating workflows. To ensure the safety of our water, there are a host of national and international regulators such as the US Environmental Protection Agency (EPA), World Health Organization (WHO), and the European Union (EU) that demand stringent testing methods for drinking water and wastewater. Those methods often call for fast implementation and lengthy processes, as well as high sensitivity and reliable instrumentation. This paper explains how your ICP-MS, ICP-OES, and LC-MS-MS workflows can be optimized for compliance with the latest requirements for water testing set by regulations like US EPA methods 200.8, 6010, 6020, and 537.1, along with ISO 17294-2. It will discuss the challenges faced by regulatory labs to meet requirements and present field-proven tips and tricks for simplified implementation and maximized uptime.
