In the first of this new column, Michael Balogh takes a look at source design and the strengths of multimode ionization, such as its ability to switch at high speeds between electrospray and atmospheric-pressure chemical ionization.
High-Throughput 4D TIMS Method Accelerates Lipidomics Analysis
April 25th 2024Ultrahigh-pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) had been previously proposed for untargeted lipidomics analysis, but this updated approach was reported by the authors to reduce run time to 4 min.