Starting Out Right, Part IV–Additional Variables to Control Selectivity

LCGC North America, March 2000, Volume 18, Issue 3
Pages: 286–294

Columns | <b>Column: LC Troubleshooting</b>

In part III of this column series, John Dolan demonstrated that systematic variation of the solvent strength can change selectivity and retention, and changing solvent type can amplify the effect. This month, he looks at three additional parameters (pH, temperature, and column type) for adjusting selectivity.