The current trend in laboratory equipment design is the miniaturization of laboratory instruments. Smaller-scale HPLC instruments offer benefits that cannot be matched by analytical-scale equipment, especially in the areas of portability, reduced fluid volumes, and reduced operating costs. Yet, the miniaturization of laboratory equipment has brought with it a unique set of challenges, including transferring methods to compact LC.
Capillary LC expands the use of LC to applications not currently done using conventional LC in a wide array of application areas, including pharmaceutical, food and beverage, petrochemical, environmental, and oil and gas. Greg Ward, Axcend’s CEO wrote, “Customers want an HPLC system with a small footprint, low flow rates and green chemistry.” Join his podcast where he shares method transfer in these application areas.
Nano-liquid chromatography-high-resolution tandem mass spectrometry (nano-LC-HRMS/MS) reveals saliva protein shifts before and after multiple sclerosis therapy.
Max Besenhard explains how hybrid mechanistic and machine learning models can make HPLC method development quicker, more robust and ready for autonomous digital twins.