Polymer Laboratories, now a part of Varian, Inc., has published an application note on Universal quantification using ELS detection and real-time response control. The ability of the Varian 385-LC to overcome solvent enhancement effects during gradient elution makes it ideal for quantifying unknown compounds. This application note shows that combined with the improved sensitivity to semi-volatile compounds at sub-ambient temperature, the Varian ELSD offers a simple and accurate solution to universal quantification.
Understanding FDA Recommendations for N-Nitrosamine Impurity Levels
April 17th 2025We spoke with Josh Hoerner, general manager of Purisys, which specializes in a small volume custom synthesis and specialized controlled substance manufacturing, to gain his perspective on FDA’s recommendations for acceptable intake limits for N-nitrosamine impurities.