Application Notes: Pharmaceuticals
Pickering Laboratories - Amino Acid Analysis by European Pharmacopeia to Support Coronavirus Research
Pharmaceutical companies worldwide are currently searching for vaccines, therapeutic agents, and prophylactics to combat COVID-19. The focus on biologic drugs during the current pandemic highlights the crucial role amino acids analysis plays in research and production of pharmaceuticals.
Waters - An Anion-Exchange Chromatography Method for Monitoring Empty Capsid Content in Adeno-Associated Virus Serotype AAV8
The single-stranded DNA (ssDNA) content of AAV capsids in AAV-based gene therapy preparations impacts the efficacy of this treatment modality. We demonstrate that AAV8 capsids without and with full length ssDNA can be separated and their relative abundances determined on a Waters Protein-Pak Hi Res Q strong anion-exchange column.
Cell Protein Analysis Using Agilent AssayMAP Bravo
An HCP analysis workflow including the Agilent AssayMAP Bravo platform for automated sample preparation, 6545XT AdvanceBio LC/Q‑TOF for LC-MS/MS analysis
Determination of Nitrosamine Impurities Using Ultivo
A method describing the detection of 12 potentially mutagenic nitrosamine impurities found in sartan drugs using the Ultivo LC/TQ
Improve ROI with Integrated LC–MSD Solution
Use interactive calculators included in this whitepaper to determine the incremental economic value of the Agilent 1260 Infinity II Prime LC and InfinityLab LC/MSD iQ.
A One Column Solution for Residual Solvents and Terpene Analysis in Cannabis
In this application, we look at the determination of residual solvents and terpenes in cannabis by GC–FID using the Zebron™ ZB-624plus™ GC column.
Improved USP Chlorhexidine Gluconate Assay on YMC-Triart C18 and YMC Meteoric Core HPLC Packing Materials
This application note details improved HPLC assay methods for chlorhexidine gluconate on hybrid-silica and core-shell C18 stationary phases.
Analysis of Inorganic Anions Using the New Hydroxide-Selective Column
Better, Faster Method Development at Janssen Pharmaceuticals
Learn how Janssen cut method-development time by 80% while improving quality 25-fold by upgrading their hardware and using method-development software.
Part 2: A Conversation with Monica Cahilly: Current Perspective for CGxP Compliance
• Special considerations when updating software • Data integrity challenges in the cloud environment • Implications of moving to the cloud with respect to audits