Ion mobility spectrometry has found commercial success as a homeland security tool in the field detection of explosives, drugs, and chemical weapons. Other common uses for the technique have been in the pharmaceutical industry for cleaning validation and in the analysis of biological material. The applications to be discussed in this Wednesday morning session include the combination of IMS with MS, the characterization of carbohydrate?protein binding, protein and peptide analysis, IMS-MS analyses with elevated electric field intensities, and neutral ion pair evaporation from ionic liquid nanodroplets