E-Separation Solutions
The James L. Waters Annual Symposium recognizes pioneers in instrumentation development and explores the origins, development, implementation, and commercialization of important scientific instrumentation. This Monday afternoon session was arrranged for by Janeth K. Pifer and Arnit Ghosh of PPG Industries (Pittsburgh, Pennsylvania). Pifer is slated to preside over the session.
Session 760
Room 205A, 2:00 p.m.
The James L. Waters Annual Symposium recognizes pioneers in instrumentation development and explores the origins, development, implementation, and commercialization of important scientific instrumentation. This Monday afternoon session was arrranged for by Janeth K. Pifer and Arnit Ghosh of PPG Industries (Pittsburgh, Pennsylvania). Pifer is slated to preside over the session.
The session will begin with brief introductory remarks from Janeth K. Pifer, followed by the first presentation, “A Historical Review of the Moving-Belt Interface in LC/MS,” to be given by William H. McFadden, who retired from Finnigan Instruments in 1989. McFadden joined Finnigan Instruments in 1973 and developed the moving-belt interface for LC–MS.
The next presentation in the session is titled “The Rise and Fall of Thermospray as a Practical Interface Between LC and MS” and will be delivered by Marvin L. Vestal of Virgin Instruments Corporation (Sudbury, Massachusetts). Vestal has held positions in various analytical instrumentation companies, including Vestec Corporation, PerSeptive Biosystems, and Applied Biosystems as well as his current position of CEO and CSO for Virgin Instruments.
Jack Henion of Advion BioSciences (Ithaca, New York) will present the next talk, titled “The Evolution of Direct Liquid Introduction (DLI) LC/MS to Ion Spray LC/MS.” An Emeritus Professor of Toxicology at Cornell University, Henion has researched many areas of LC–MS with a focus on atmospheric pressure ionization sources.
The symposium’s final presentation will be given by Thomas R. Covey of MDS Analytical Technologies/Sciex (Concord, Ontario, Canada) and is titled “The Rise and Fall of LC/MS Interface Instrumentation.” Covey is part of a group that focuses on innovations in mass spectrometry. His Ph.D. research at Cornell University involved LC–MS interfaces and their applicability to real-world problems.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Investigating Plastic Contamination in Olive Oil with GC–MS/MS
January 17th 2025The objective of this study was to investigate contamination by 32 plasticizers in olive oil throughout its production and packaging process. Separation and detection were carried out by gas chromatography tandem mass spectrometry (GC–MS/MS), without the need for pre-concentration steps.
Top Execs from Agilent, Waters, and Bruker Take the Stage at J.P. Morgan Healthcare Conference
January 16th 2025The 43rd Annual Healthcare J.P. Morgan Healthcare Conference kicked off in San Francisco earlier this week. Here’s what top executives from Agilent, Bruker, and Waters, discussed during the event.