This special article series highlights the work of young analytical chemists.

The Next Generation

Columns

Articles

Multidimensional liquid chromatography (MDLC) methods have revolutionized the characterization of complex drug modalities like antibodies–drug conjugates, antisense oligonucleotides, and small interfering RNA therapeutics.

Cracking the Code of Complex Drug Modalities via Multidimensional Liquid Chromatography Coupled to Mass Spectrometry

Two-dimensional LC, with advanced modulation techniques, can advance the analysis of advanced polymeric materials, assisting in characterizing copolymer composition heterogeneity and identifying ingredients in complex products.

Gaining New Insights in Advanced Polymeric Materials Using Comprehensive Two-Dimensional Liquid Chromatography

Examples from food science illustrate the usefulness of chemometrics techniques like pattern recognition, regression, and classification.

Enter the Matrix: Improving the Interpretation of Separations Data Using Chemometrics in Analytical Investigations

HPLC is emerging as the preferred analytical method for potency testing of cannabinoids, but fundamental work is needed to solve critical issues and contribute to advancing knowledge.

Perspectives and Pitfalls in Potency Testing of Cannabinoids by High Performance Liquid Chromatography (HPLC)

Compact instrumentation offers important advantages for many workflows, as illustrated by these examples.

The Next Generation | Columns