April 2021

Click the link above to open The Column April 2021 Europe & Asia issue, Volume 17, Number 4, in an interactive PDF format.

Click the link above to open The Column April 2021 North American issue, Volume 17, Number 4, in an interactive PDF format.

In the first of the series, Mariosimone Zoccali, discusses the development of a powerful analytical method to analyze important bioactive molecules using online SFE–SFC–QqQ-MS.

Incognito considers the future of laboratory training, questions the quality of current practices, and assesses the “easy wins” that can be learned across industries.

Elmar Piel’s pioneering work was pivotal to the development of modern-day high performance liquid chromatography (HPLC).

The benefits of a robustness assessment for the analysis of a NIST mAb using a wide pore C4 LC column are described.

Researchers from the University of Copenhagen have developed a novel, sensitive, and reliable analytical method to analyze phytotoxins in environmental matrices using RPLC–ESI‐HRMS.

Quantification of Tau proteoforms in cerebrospinal fluid (CSF) could be useful to diagnose neurodegenerative diseases. LC–MS/MS results can help explain the underlying molecular mechanisms of disease evolution.

This instalment describes the interplay between column length, pore size distribution, and particle size to optimize GPC/SEC separations.