January 2022 | LCGC Europe

Analysis of Proteins, Biologics, and Nanoparticles in Biological Fluids Using Asymmetrical Flow Field-Flow Fractionation

January 01, 2022

Peer Reviewed

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Aspects of applying AF4 to plasma, serum, milk, and cerebrospinal fluid in the field of analysis and characterization of proteins, biologics, and nanoparticles in biological fluids are reviewed.

Essentials of LC Troubleshooting, Part 1: Pressure Problems

January 01, 2022

LC Troubleshooting

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Some “LC Troubleshooting” topics never get old because there are some problems that persist in the practice of LC, even as instrument technology improves over time.

Is Golay’s Famous Equation for HETP Still Relevant in Capillary GC? Part 1: A Common View of HETP

January 01, 2022

GC Connections

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In this instalment we take a close look at Golay’s famous equation that most people see as relating HETP (height equivalent to a theoretical plate) to the carrier gas flow rate or average linear gas velocity in a capillary column.

The QuEChERSER Mega Method

January 01, 2022

Sample Preperation Perspectives

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QuEChERS has recently been updated to QuEChERSER (“more than QuEChERS” or also “efficient and robust”) to better take advantage of the features provided by modern MS-based detection tools.

Liquid Chromatography–Mass Spectrometry Analysis of Hop-Derived Humulone and Isohumulone Constituents in Beer: The Bitter Truth of Hops Utilization During Brewing

January 01, 2022

Food Analysis

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A rapid LC–MS method using ESI coupled with SIM-MS for analysis of humulone and isohumulone content in beer is described.