July / August 2022 | LCGC Europe

Py-GC-MS Investigation of Pyrolysis Behaviours and Decomposition Products of α- and β-2,7,11-Cembratriene-4,6-Diols

August 01, 2022

Peer Reviewed

35

07

The study of the thermal behaviour and pyrolysis products of these terpenoids could possibly suggest flavour precursors that could be used to provide specific flavours to tobacco.

Development of a System Suitability Test for Two-Dimensional Liquid Chromatography (2D-LC)

August 01, 2022

LC Troubleshooting

35

07

As 2D-LC becomes used more widely and in regulated laboratory environments, development and implementation of SSTs will be critical for successful routine use of the 2D-LC technique.

Nonlinear Predictive Modelling Enables In Silico Optimization of Chromatographic Methods for Complex Stationary Phase‑Analyte Interactions

August 01, 2022

Pharmaceutical Perspectives

35

07

To reach satisfactory results in terms of accurate retention time prediction, new in silico optimization approaches must be considered.

Quo Vadis Analytical Procedure Development and Validation?

August 01, 2022

Questions of Quality

35

07

What do the draft publications ICH Q2(R2) and Q14 for analytical procedure validation and development mean for a regulated GMP laboratory?

Improved Performance of Ultrahigh-Pressure Liquid Chromatography–Mass Spectrometry (UHPLC–MS) Hyphenated Systems

August 01, 2022

Column Watch

35

07

An UHPLC–MS research prototype instrument was built to improve the resolution power and the usability of conventional LC–MS hyphenated instruments for routine analyses in pharmaceutical applications.

Instrumental Innovations 2022

August 01, 2022

Features

35

07

A compilation of profiles highlighting what leading chromatography vendors are showcasing at live and virtual events this year.