LCGC Europe-06-01-2008

Successful gas chromatography (GC), akin to many other disciplines, requires regular attention to a number of routine procedures. Chromatographers, similar to anyone else, develop habits in their daily work. Some of these help create a successful laboratory environment, while others can be ineffective or worse, can create more problems than they solve. This month, "GC Connections" presents a few of the best and worse laboratory habits.

20th International Symposium on Chirality ISCD-20 2008, Geneva Switzerland

What do you do when the method can't be reproduced?

Many HPLC analyses could be performed at lower expenditure. This could involve a combination of reducing the analysis time, reducing the resolution between critical peaks, and lowering the consumption of mobile phase. Successfully optimizing the method in such instances - as well as in situations where it is necessary to transfer the method to another laboratory that lacks the same selection of columns - can save the analyst time and money.

Add-on instrument control available; Software for mass spectrometry imaging; GC–MS reprocessing software; Software for multi-channel pipette calibration process

This article investigates the different methods that can be used to compare the performance of liquid chromatography (LC) columns to assess the advantage of using them at high pressures and/or high temperatures. The main focus is on the kinetic plot method. This method, which is based on two simple equations, allows the user to transform the more common Van Deemter curve into a curve describing the ultimate separation speed as a function of the required plate number, or the required peak capacity or the required resolution.

You may work in a chromatography laboratory to quality standards but do you work to Good Laboratory Practice? Probably not...

Hian Kee Lee speaks with Alasdair Matheson about "environmentally friendly" sample preparation techniques.