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© 2023 MJH Life Sciences™ and Chromatography Online. All rights reserved.
January 01, 2023
Column: LC Troubleshooting
When considering different ways to improve an established LC method, it helps to start by reviewing some essential concepts.
Column: Sample Prep Perspectives
Continued development of needle-trap extraction (NTE) has expanded
its versatility in applications such as disease diagnosis, aerosol-bound analytes, and breath analysis.
Column: GC Connections
The common measures of stationary phase polarity—McReynolds constants and the polarity scale—are not always accurate predictors of retentiveness or selectivity in GC.
Column: Focus on Biopharmaceutical Analysis
A drug stability program is a fundamental part of ensuring product quality,
safety, and efficacy. Here, we summarize essential guidelines, differences between large- and small-molecule stability, and the analytical methods used.
Robots outperform humans in five areas, and thus can be particularly beneficial for performing sample preparation for HPLC.
A harmonization of all conventional hold-up volume methods was successfully applied to RPLC, HILIC, AEX, and RP-AEX mixed-mode chromatography, regardless of the mobile phase.