LCGC North America-01-01-2002

The authors describe a new approach for verifying robustness testing in HPLC.

"GC Connections" examines the basics of peak integration for quantitation in chromatography with an emphasis on fast separations.

This article describes the use of phases with extended polar selectivity to reduce analysis time for wide-polarity-range samples such as an insecticide, simulated carboxylic acid degradants, and phthalate esters.

Tim Wehr looks at the use of fast LC}MS for high-throughput analysis of pharmaceutical compounds.

The authors examine a case in which ion suppression compromised method performance.

Leslie Ettre discusses the factors that led to the invention and development of the flame ionization detector for GC.

This month's installment discusses the practical aspects of the scale-up process and the problems and costs of preparative separations within a mid-sized pharmaceutical company.