LCGC North America-01-01-2002

LCGC North America

A Geometric Approach to Robustness Testing in Analytical HPLC

January 01, 2002

Article

20

1

The authors describe a new approach for verifying robustness testing in HPLC.

Data Handling for Fast Chromatography — Peak Integration

January 01, 2002

GC Connections

20

1

"GC Connections" examines the basics of peak integration for quantitation in chromatography with an emphasis on fast separations.

The Benefits of Reversed Phases with Extended Polar Selectivity in Analyzing Wide-Polarity-Range Samples

January 01, 2002

Article

20

1

This article describes the use of phases with extended polar selectivity to reduce analysis time for wide-polarity-range samples such as an insecticide, simulated carboxylic acid degradants, and phthalate esters.

Fast LC for High-Throughput LC–MS

January 01, 2002

Directions in Discovery

20

1

Tim Wehr looks at the use of fast LC}MS for high-throughput analysis of pharmaceutical compounds.

Ion Suppression in LC–MS–MS — A Case Study

January 01, 2002

LC Troubleshooting

20

1

The authors examine a case in which ion suppression compromised method performance.

The Invention, Development, and Triumph of the Flame Ionization Detector

January 01, 2002

Milestones In Chromatography

20

1

Leslie Ettre discusses the factors that led to the invention and development of the flame ionization detector for GC.

Practical Aspects of Preparative HPLC in Pharmaceutical Development and Production

January 01, 2002

Column Watch

20

1

This month's installment discusses the practical aspects of the scale-up process and the problems and costs of preparative separations within a mid-sized pharmaceutical company.