LCGC North America-01-01-2002

Article
LCGC North America

January 01, 2002

The authors describe a new approach for verifying robustness testing in HPLC.

GC Connections
LCGC North America

January 01, 2002

"GC Connections" examines the basics of peak integration for quantitation in chromatography with an emphasis on fast separations.

This article describes the use of phases with extended polar selectivity to reduce analysis time for wide-polarity-range samples such as an insecticide, simulated carboxylic acid degradants, and phthalate esters.

Directions in Discovery
LCGC North America

January 01, 2002

Tim Wehr looks at the use of fast LC}MS for high-throughput analysis of pharmaceutical compounds.

LC Troubleshooting
LCGC North America

January 01, 2002

The authors examine a case in which ion suppression compromised method performance.

Milestones In Chromatography
LCGC North America

January 01, 2002

Leslie Ettre discusses the factors that led to the invention and development of the flame ionization detector for GC.

This month's installment discusses the practical aspects of the scale-up process and the problems and costs of preparative separations within a mid-sized pharmaceutical company.