LCGC North America-01-01-2008

Thermo Fisher Scientific Partners with China Doping Control Center; Millipore to Provide "Stem Cell Tested" Products; Hood Wins Pittcon Heritage Award

The second part of the series takes a look at what happens to the pneumatic operating conditions and chromatography with GC oven temperature programming of a wide-bore column.

This month's "LC Troubleshooting" installment examines the possible reasons your retention times could have changed. If the root cause can be identified and corrected, no adjustment in flow rate will be necessary.

This article describes the factors that affect the selection of columns for two-dimensional (2D) LCxLC separations.

Work done 60 years ago at the University of Innsbruck (Austria), representing the start of gas chromatography, is outlined in this month's column.

Solid-phase extraction (SPE) has been available comercially for over twenty years and is still finding new applications. Growth of this technique seems to be largely a function the vendors' capability to provide specific application support, especially in clinical sciences, pharmaceuticals, toxicology, pesticides, and residues analysis.

In this installment of "Column Watch," Ron Majors examines the various approaches to increasing the speed of high performance liquid chromatography (HPLC) separations.

Comprehensive GCxGC was employed for the separation of ICH and USP 1, 2, and 3 pharmaceutical solvents. The significantly improved peak capacity in GCxGC allows a single method for any combination of solvents and mitigates interference due to impurities in the solvents, diluents, analyte matrices, and from column or septum bleed, through the increased separation space.