LCGC North America-01-01-2015
LCGC North America
Seven Things to Avoid in the Liquid Chromatography Laboratory
January 01, 2015
LC Troubleshooting
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1
Have a problem with your LC system? Maybe applying a little "DDT (Don't Do That)" may help.
Pyrolysis for the Preparation of Macromolecules and Analysis by Gas Chromatography
January 01, 2015
Sample Prep Perspectives
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When pyrolyzed, macromolecules will decompose into smaller fragments that can have the appropriate volatility for gas chromatography (GC) separation and analysis.
GC Detectors: From Thermal Conductivity to Vacuum Ultraviolet Absorption
January 01, 2015
GC Connections
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Some might consider gas chromatography (GC) a mature technique. However, several substantial advances in GC technology in the past few years have proven that there is still room for innovation.
Quantifying Small Molecules by Mass Spectrometry
January 01, 2015
MS – The Practical Art
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The use of a mass spectrometer in quantitative analysis exploits its exquisite selectivity and sensitivity as a detector, allowing a signal to be ascribed to a particular chemical entity with high certainty, even when present in a sample at a low concentration.
Challenges in the Determination of Protein Aggregates, Part I
January 01, 2015
Biotechnology Today
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Most analytical approaches used for the determination of low-molecular-weight noncovalent aggregates in protein pharmaceuticals suffer from important limitations. This first part of this two-part column series discusses those limitations.
In Memoriam: Professor Georges A. Guiochon
January 01, 2015
Featured Article
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On October 21, 2014, University of Tennessee Distinguished Scientist Georges Andre Guiochon succumbed to neuromuscular failure caused by post-polio syndrome. Here, we pay tribute to his remarkable career and life.
HPLC Detector Selection — What, Where, When, and How
January 01, 2015
The Essentials
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The ideal UV detector would allow us to monitor the presence of our target analytes without influence from the background eluent and sample matrix components that may be present in the detector measuring cell at the same time
Large-Volume Injection LC–MS-MS Methods for Aqueous Samples and Organic Extracts
January 01, 2015
Peer-Reviewed Article
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Environmental sample analysis by large-volume injection (LVI) in combination with liquid chromatography–tandem mass spectrometry (LC–MS-MS) is described for polar and nonpolar analytes in both aqueous samples and organic extracts.
Vol 33 No1 LCGC North America January 2015 Regular Issue PDF
January 01, 2015
Issue PDF
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Click the title above to open the LCGC North America January 2015 regular issue, Vol 33 No 1, in an interactive PDF format.