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LCGC North America-03-01-2003

LCGC North America

Critical Pairs in Column Chromatography: A Primer for Pharmaceutical Method Validation

March 01, 2003

Article

21

3

This article reviews several common applications of the critical-pair approach to column chromatography as it is applied under pharmaceutical guidelines and validation strategies.

Handling Fast Peaks

March 01, 2003

GC Connections

21

3

John Hinshaw examines the effects of system time constants and sampling rates on apparent peak shapes and areas.

New Chromatography Columns and Accessories at the 2003 Pittsburgh Conference, Part I

March 01, 2003

Column Watch

21

3

The first of two columns about new chromatography columns, accessories, and sample preparation products introduced at Pittcon 2003.

Affinity Selection Techniques for Proteomic Studies

March 01, 2003

Directions in Discovery

21

3

Two solutions to the problem of obtaining quantitative information about protein expression are to couple two or more chromatographic modes to increase resolution and to use affinity selection techniques.

LC Columns — The Top-10 List

March 01, 2003

LC Troubleshooting

21

3

John Dolan provides 10 tips for the proper care and use of LC columns.