September 2021 | LCGC North America

Analyzing Per- and Polyfluoroalkyl Substances in Drinking Water Using EPA Methods 533 and 537.1 with Semi-Automated Solid-Phase Extraction (SPE)

September 01, 2021

Columns

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There is a need for fast and reliable PFAS analyses to monitor drinking water quality. We report on the use of semi-automated sample preparation with EPA methods 533 and 537.1, assessing performance and processing time.

The Future of Separation Science: Goodbye Old Friends

September 01, 2021

Viewpoints

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Are the days numbered for long linear runs of univariate data in separation science?

Novel 3D-Printing Method to Create Liquid Chromatography Columns

September 01, 2021

Column Watch

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Three-dimensional (3D) printing shows promise for creating stationary phases with tailored geometries. We present a method that overcomes limitations of other approaches, and can produce columns with a feature resolution of 10 μm.

Evaluating Two Dioscin-Based Silica Stationary Phases and their Application to Achiral and Chiral Separations

September 01, 2021

Peer Reviewed Articles

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Improved analysis of pharmaceutical and natural medicine products requires advances in reversed-phase LC stationary phases. We examine two synthesized stationary phases with applicability in quality control and chiral separation for analysis of natural products.

But My Peaks Are Not Gaussian! Part II: Physical Causes of Peak Asymmetry

September 01, 2021

LC Troubleshooting

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In a continuing series on peak shapes, we focus on potential physical causes of asymmetry, including column packing, changes in the packed particle bed, and accumulation of debris in the column.

Remember Harold McNair: Three Fundamental Areas of Understanding in Gas Chromatography

September 01, 2021

Column: GC Connections

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The late Harold McNair had a remarkable 60-year career as a chromatographer. He taught us many valuable lessons, three of which we discuss here.

Origins of Sample Preparation Technologies

September 01, 2021

Column: Sample Prep Perspectives

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We look at five modern treatments of chromatographic sample extraction, explaining their initial conception and development to shed light on their current roles as analytical tools.