LCGC North America-10-01-2011

Nano LC is now widely applied in proteomics, and also is robust enough for application in fields such as pharmaceutical analysis.

An exploration of LDTD-MS-MS and how it compares to HPLC–MS-MS techniques in terms of sensitivity, robustness, and speed in an in-vivo drug discovery application

A limited set of stationary phases can separate a wide variety of molecules and maintain good peak shape without mobile-phase additives.

How do you react to symptoms that indicate your liquid chromatography column has major problems?

A clear understanding of the chemical system of the sample in headspace - and how temperature and peak volume affect peak areas, sensitivities, and repeatability - will improve headspace analysis.

Click the title above to open the LCGC North America October 2011 regular issue, Vol 29 No 10, in an interactive PDF format.