LCGC North America-11-01-2002

LCGC North America

Characterizing Reversed-Phase Column Selectivity

November 01, 2002

Column Watch

20

11

Guest authors Lloyd Snyder and John Dolan describe a method for determining reversed-phase column selectivity.

A Compendium of GC Terms and Techniques

November 01, 2002

GC Connections

20

11

John Hinshaw updates his glossary of GC terms and techniques.

Preparative Chromatography with Improved Loadability

November 01, 2002

Article

20

11

The authors show that the loadability and throughput of ionizable compounds can be enhanced by using hybrid packings.

Determination of Aroclor 1248 in Rat Plasma and Liver Matrices: Recovery and Quantification Considerations

November 01, 2002

Article

20

11

The author determines the uncertainty in the quantification of four rat liver samples by applying a statistical evaluation.

Requirements for Validating a Capillary Isoelectric Focusing Method for Impurity Quantitation

November 01, 2002

Validation Viewpoint

20

11

The guest authors present a strategy for validating a capillary isoelectric focusing method intended to quantitate impurities in a protein drug substance.

Mobile-Phase Buffers, Part I — The Interpretation of pH in Partially Aqueous Mobile Phases

November 01, 2002

LC Troubleshooting

20

11

Guest author G. William Tindall discusses pH measurements in aqueous solutions and the changes that occur when organic solvent is added.